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BioProcess International Conference & Exhibition
Managing Manufacturing Networks Product Lifecycle Management
Cell Culture & Upstream Processing Recovery & Purification
September 20-24, 2010 * Providence, Rhode Island, USA New Programming for Vaccines, Raw Material & Suppliers, Emerging Analytical Requirements

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Event Information

Conference: September 20 - 24, 2010 · Exhibition: September 21-23, 2010 · Rhode Island Convention Center · Providence, RI

Document Title

Hydroxyapatite for Biomanufacturing

Hydroxyapatite for Biomanufacturing

Tuesday, September 21, 2010 - Main Conference

7:00
Registration and Coffee

Advancements and Case Studies of Hydroxyapatite for Biomanufacturing

8:00 am-12:00 pm

We are pleased to bring you a half-day technology workshop featuring many of the world's leading authorities to discuss new advancements and applications in separation science using hydroxyapatite and related materials. In this session, we will discuss modern techniques for separation and analysis of immunoglobulins, enzymes, and related biomolecules from micropreparative to industrial scale. Speakers will present case studies and the latest developments using hydroxyapatite in the manufacturing of biopharmaceuticals. A roundtable discussion will conclude this workshop highlighting key biomanufacturing topics and challenges today.

Topics & Presenters:

8:15-8:45
Dissociation of Antibody: DNA Complexes by Hydroxyapatite
Pete Gagnon, Chief Scientific Officer, Validated Biosystems

8:45-9:15
Ceramic Hydroxyapatite Usage in Process Manufacturing
Norbert Schuelke, Ph.D., Associate Director, Millennium Pharmaceuticals, Inc.

9:15-9:45
Best Practices for Packing Ceramic Hydroxyapatite at Process Scale
Kim Brisack, M.S., Staff Scientist, Bio-Rad Laboratories

10:15-10:45
A New, Robust Method for Protein Elution from Ceramic Hydroxyapatite
Mark A. Snyder, Ph.D., Process R&D Applications Manager, Bio-Rad Laboratories

10:45-11:15
Packing Ceramic Fluoroapatite at Multiple Process Scales
Jaclyn Shaffer, R&D Associate II, MedImmune

11:15-12:00
Roundtable Discussion
  • Downstream process of monoclonal antibodies
  • Scale-up and optimization of hydroxyapatite, handling and qualification testing
  • Chemical robustness of ceramic hydroxyapatite
  • Application of hydroxyapatite in vaccine production

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