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Antibody Engineering & Therapeutics

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Supporting the Scientific Community in Development Therapeutic Antibodies for Over 2 Decades

December 08-12, 2013 · Hyatt Regency Huntington Beach Resort & Spa · Huntington Beach, CA

Event Overview

Event Overview

Supporting the Scientific Community in Development Therapeutic Antibodies for Over 2 Decades

Announcing IBC's Antibody Engineering & Therapeutics, just for 2013, is moving to a refreshing new beachfront location in Huntington Beach, CA. This gorgeous venue is easily accessible by Los Angeles (LAX), Orange County (SNA) and Long Beach (LGB) airports! Join us December 8-12, 2013 at the world's leading forum for the exchange of cutting-edge protein engineering science and antibody therapeutics now in development.

» We are now accepting speaker proposals for 2013 - submit your topic idea today!

Just Announced:
Early Confirmed Keynote Speakers

Leroy Hood, M.D., Ph.D.

Leroy Hood, M.D., Ph.D.
President
Institute for Systems Biology

Douglas A. Lauffenburger, Ph.D.
Ford Professor of Biological Engineering, Chemical Engineering, and Biology; Head, Department of Biological Engineering, Massachusetts Institute of Technology

Merging Science with Technology to Accelerate Antibodies to Market...

Now in its 24th year, Antibody Engineering & Therapeutics has earned its reputation by consistently offering the most current academic research findings and most recent industry updates. Our attendees come back year after year for the information they need to stay abreast of the latest scientific trends in the antibody field. World-renowned scientists from across the globe convene at this event to share best practices and new approaches to exploit antibodies for developing novel medicines and vaccines. Learn about both the basic science of antibody engineering and the latest preclinical/clinical data, including safety and efficacy studies of the most cutting-edge antibody therapeutics now in development. We hope to see you this December in Huntington Beach!

2012 Conference Meeting Summary

2012 Conference Meeting Summary

Get the "inside look" of the 2012 meeting with this post conference report written by attendees and featured in mAbs Journal.

Authors: Peter-Christian Klöhn, Ulrich Wuellner, Nora Zizlsperger, Yu Zhou,Daniel Tavares, Sven Berger, Kirstin A. Zettlitz, Gabriele Proetzel, May Yong, Richard H.J. Begent, and Janice M. Reichert

» View the Report (PDF)

Looking Into Antibody Engineering & Therapeutics 2013

Here is a Sneak Peek at Some of the Exciting New Topics to be Covered:

  • Systems biology/systems immunology of antibodies - how is everything connected?
  • Alternative antibody formats: Mixtures, oligoclonals and polyclonals
  • Anatomy/physiology of antibody distribution in different biological systems
  • Intracellular antibodies
  • Antibody library design and affinity maturation techniques
  • Deep-sequencing of antibody responses
  • Linkers and conjugation strategies for antibodies
  • Immunomodulatory antibodies for cancer therapy and other diseases
  • Non-cancer antibodies: infectious disease, non-malignant disease, autoimmune, CNS
  • Clinical successes and failures - what have we learned?
  • Antibody effector function
  • Immunogenicity
  • Antibodies as probes for intracellular post-translational modifications
  • Cell biology of membranes, receptors and signaling leading to new targets for antibodies
  • The Interface between humoral and cell-mediated immunity in cancer
  • Non-antibody scaffolds
  • Tumor targeting strategies: Why does so little antibody get into the tumor? How to improve?
  • Physiology of tissue degradation
  • Dealing with off target toxicity and PK/PD of proteins
  • Clinical design strategies for antibody drugs, including phase 1 and phase 0 trial design
  • Biomarkers, imaging and companion diagnostics for antibody drugs
  • Building in manufacturability to your antibodies, optimization techniques for production
  • Patient enrichment strategies for mAb therapies
  • Antibodies by design: bioinformatics and modeling strategies to develop target-biased libraries
  • Molecular engineering and design strategies
  • Antibody administration: local and targeted delivery, alternative delivery approaches
  • Gene-based Ab Expression - the intersection of Abs and gene therapy
  • Antibodies in a complex environment
  • From receptor biology to therapy
  • Antibody-drug conjugates: preclinical and clinical updates
  • Alternative antibody scaffolds, multifunctional antibodies, bispecifics, combinations
  • Antibody activity and animal models
  • Modulating half-life of antibody therapeutics
  • Development status of early stage therapeutic antibodies
  • Diagnostic applications of antibodies
Next Generation Protein Therapeutics Summit