Institute for International Research

The ONLY Event in North America this Year Dedicated to Covering the Full Spectrum of Advances in Cell Line Development!

Keynote Presentations: How do ER Stress and Oxidative Stress Impact Protein Production? Randal J. Kaufman, Ph.D., Warner-Lambert/Parke-Davis Distinguished Professor of Biological Chemistry and Internal Medicine, Howard Hughes Medical Institute, University of Michigan Medical Center Genomic and Proteomic Tools to Elucidate How Mammalian Cell Factories Achieve High Level Productivity David James, Ph.D., Professor of Bioprocess Engineering, Department of Chemical and Process Engineering, University of Sheffield, United Kingdom Featured Presentation: Glycosylation and Protein Engineering: Effect on Activity, Stability and Functionality Roy Jefferis, Ph.D., Professor of Molecular Immunology, Division of Immunity & Infection, University of Birmingham, United Kingdom Team Discounts Register 3 at the Standard Rate and the 4th Goes Free! Save up to $2099. When three members of the same company register and pay for the conference at the same time, the fourth attends for FREE! This discount is valid only based on the standard rate (after May 23, 2008). For more information on the group rates or to register your group, please call customer service at (800) 390-4078.

Recent advances in cell line engineering have led to dramatic improvements of upstream processing yields exceeding 5g per L. The latest strategies for achieving this progress while successfully shortening development lead times and workflows are highlighted at IBC's 4th Cell Line Development and Engineering.

IBC's distinguished scientific advisory committee have developed a cutting-edge program that examines how companies are successfully balancing speed with productivity during cell line selection and development. These achievements will be highlighted during several case studies that demonstrate the rapid generation, screening and development of stable and highly-productive cell lines. In addition, industry experts will explore the enormous potential of applying genomic and proteomic tools in cell line engineering.

Is your goal to shorten timelines while increasing expression levels, improving product quality, and enhancing manufacturability, through total process optimization?

If so, don't miss the only event in North America this year that will bring together scientists, engineers, and executives in cell line development with similar challenges and objectives. Please review the agenda now and register early for significant savings.

Expanded focus on today's important issues including:

• Successfully streamlining cell line development processes while simultaneously shortening timelines
• Proven strategies for the rapid generation of highly productive cell lines
• Screening of clones for improved cell line manufacturability
• Advantages of protein production using alternative expression systems
• Approaches that predict stability/instability of protein expression in engineered cell lines
• Application of genomic, proteomic and metabolomic tools to improve cell line development
• Detection of immunogenicity, glycosylation and post-translational modifications and prevention of their impact on quality